Handbook of Pharmaceutical Excipients – Ninth Edition

Guide to the properties for excipients, their safe use and application.

Description

Extensive information on the uses and properties of excipients. Including pharmacopeias, patents, manufacturer’s data with grade-specific differences. Pharmaceutical Excipients bring together Global information sources and expert observations

The 400+ monographs are also thoroughly cross referenced and indexed to allow their identification by chemical, non proprietary or trade names.

Extensive content updates in this edition include:

• Over 420 fully referenced excipient monographs, many including IR, Raman, and NIR spectra
• 13 new monographs including several amino acids and hydrated silicon dioxide
• 250 existing monographs reviewed

New chapters include excipient selection for orally inhaled and injectable formulations.

New Formulation Considerations and Related Information chapters on:

• Functional Categories of Pharmaceutical Excipients
• Pharmaceutical Excipients in Pediatric Formulations
• The Selection of Excipients for Oral Solid Dosage Forms
• The Selection of Excipients for Injectable Formulations
• Formulation Considerations for Orally Inhaled Dosage Forms
• Reactive Components in Pharmaceutical Excipients
• Biological Effects of Pharmaceutical Excipients
• The Use of Counter-ions and Co-formers in the Creation of Salt and Co-crystal Forms of Active Pharmaceutical Ingredients (APIs)

Over 400 Monographs benefiting from a standardized, easy-to-use template including:

• pharmacopoeial information from the UK, Europe, Japan and the United States
• non-proprietary names and synonyms
• chemical name and structure, CAS Registry number, empirical formula, molecular weight
• functional category, applications and incompatibilities
• material description and typical excipient properties
• safety, stability, storage and handling information
• method of drug manufacture
• related substances
• primary references
• editorial comments

• Suppliers directory
• List of Monographs by Functional Category
• List of Related Substances
• List of Excipients by ‘E’ number
• List of Excipients by ‘EINECS’ number
• List of Excipients by ‘CAS’ number
• Pharmaceutical Excipients Assessed by the FDA Select Committee on GRAS Substances (SCOGS)